PheroTalk

PheroTalk

The World's Largest Pheromone Community

Get Real Pheromones directly from Androtics Pheromone Research at the SmartMones Pheromone Store

Questions about pheromones?
Get Fast, Friendly, No-Obligation Help from Real People at the Pheromone Hotline.
Call 1-800-671-6464 in the USA, or +01 425-786-2001 Internationally

Latest Threads ::.. Hi There, Newbie here M 28, Europe, phero combination ultimate mix ?? Diluting mones Hi Everyone! Need advice. Pheromones to Put Wife in Good Mood after Work. M/51 Traveling and loosing product Hello! Newbie here! Pheromones to Make my BF More Open and Sexual w/ Me. F/29 Pheromone mix to work with my wife about attraction, trust, affection, bonding. M/37 advice on specific combo Chemicals that interfere with pheros?


Go Back   PheroTalk > Discussion > Pheromone Theory

Register Invite Your Friends FAQ Members List Calendar Mark Forums Read

Reply
 
Thread Tools Display Modes
Old August 7th, 2009, 05:45 AM   #1
ajo41992 Male
Pheromone Experienced
  
 
ajo41992's Avatar
 
Join Date: Mar 2009
Posts: 155
Thanks: 1
Thanked 17 Times in 15 Posts
Nominated 0 Times in 0 Posts
TOTW/F/M Award(s): 0
Reputation: 166
ajo41992 has a spectacular aura about ajo41992 has a spectacular aura about
Default Effects of Synthetic Pheromones on production of Natural Pheromones

Topic: Will excessive pheromone use impair one's body to produce pheromones naturally?

Discussion: In drugs like Crystal Meth, a chemical that is normally made by the body naturally (serotonin, I believe) is taken in excessive amounts. Knowing that the body does not need to make these chemicals itself, it simply stops. This creates an addiction: a necessary bodily function stops working because a synthetic chemical was temporarily doing the work for the body. The drug then becomes NECESSARY to human activity.

Topic, restated:
Will synthetic pheromones eventually cause our bodies to stop making natural pheromones?

------
Please discuss! I'd love to get some insight on this. I'm not in any way trying to harm the business, simply trying to start a scientific discussion and begin a theory.
__________________
OWNED: A314, CTTM2, To-Go's of Shine, Honesty, Openness (2x), Jerk, AMMO, Gentleman
WISHLIST: MX292, MX272, Spaceland,
ajo41992 is offline   Reply With Quote
Old August 7th, 2009, 05:58 AM   #2
pheropro Undisclosed
Pheromone Cadet
  
 
Join Date: May 2009
Age: 36
Posts: 21
Thanks: 0
Thanked 1 Time in 1 Post
Nominated 0 Times in 0 Posts
TOTW/F/M Award(s): 0
Reputation: 11
pheropro is on a distinguished road
Default Re: Effects of Synthetic Pheromones on production of Natural Pheromones

No, it won't. The synthetic pheromones available for purchase don't go into the bloodstream, and thus, can't effect the body's ability to naturally produce anything.

Meth, on the other hand, goes into the bloodstream.
pheropro is offline   Reply With Quote
Old August 9th, 2009, 01:39 AM   #3
Fetus Farm Undisclosed
Pheromone Enthusiast
  
 
Join Date: Aug 2009
Posts: 41
Thanks: 5
Thanked 3 Times in 3 Posts
Nominated 0 Times in 0 Posts
TOTW/F/M Award(s): 0
Reputation: 13
Fetus Farm is on a distinguished road
Default Re: Effects of Synthetic Pheromones on production of Natural Pheromones

Quote:
Originally Posted by pheropro View Post
No, it won't. The synthetic pheromones available for purchase don't go into the bloodstream, and thus, can't effect the body's ability to naturally produce anything.

Meth, on the other hand, goes into the bloodstream.
That's not true. There are negative feedback loops in the body that do not directly involve vascular transport. For example, if you eat something that increases the acidity of your stomach, parietal cells respond by secreting less protons, thus normalizing the acidity of your stomach.

That's just one example. There are others. Unfortunately, I don't know the answer to ajo's question, but it seems like a valid concern.
Fetus Farm is offline   Reply With Quote
Old August 9th, 2009, 02:25 AM   #4
Xiphoid Female
Swede as Sugar
  
 
Xiphoid's Avatar
 
Join Date: Jan 2009
Location: UK
Age: 39
Posts: 1,792
Thanks: 224
Thanked 440 Times in 334 Posts
Nominated 8 Times in 7 Posts
TOTW/F/M Award(s): 0
Reputation: 1939
Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future
Default Re: Effects of Synthetic Pheromones on production of Natural Pheromones

Quote:
Originally Posted by ajo41992 View Post
Discussion: In drugs like Crystal Meth, a chemical that is normally made by the body naturally (serotonin, I believe) is taken in excessive amounts. Knowing that the body does not need to make these chemicals itself, it simply stops. This creates an addiction: a necessary bodily function stops working because a synthetic chemical was temporarily doing the work for the body. The drug then becomes NECESSARY to human activity.
This isn't entirely correct actually, well, to be honest, not correct at all.
Methamphetamine doesn't affect serotonin, it affects mainly dopamine but also noradrenaline. The drug does NOT contain dopamine though, when taking methamphetamine you aren't taking dopamine or a synthetic version thereof. You are taking a drug which reverses the direction of the post-synaptic transporters with the resultant effect being increased amounts of dopamine in the post-synaptic cleft and hence more stimulation of post-synaptic receptors. Methamphetamine also indirectly inhibits the re-uptake of the neurotransmitters.

So the drug isn't a synthetic chemical that does the same thing that dopamine does. It's a chemical that "tricks" the receptors into re-using the same neurotransmitters over & over instead of using once and metabolizing them. Your body doesn't stop producing dopamine though.
__________________
My toys; IS/a, IS/b, IS/b 5x cops, IH (1x & 2x), IO2x, IS (1x & 2x), CTTM2, A-nol, B-nol, Mx135, Mx202, Mx215, Mx250, Mx274, Mx282, Mx292, Mx300, TAA, TAC, TAF, TAH, TAL, EST, Meo-EST, P74, P78, P79, P80, P83, P85, P86, P90, P91, P93, P102, EOW, TUTH

Wishlist; TAK, P103, P107, Mx109, Mx216 Oh, and of course....more money....
Xiphoid is offline   Reply With Quote
Old August 9th, 2009, 02:38 AM   #5
Fetus Farm Undisclosed
Pheromone Enthusiast
  
 
Join Date: Aug 2009
Posts: 41
Thanks: 5
Thanked 3 Times in 3 Posts
Nominated 0 Times in 0 Posts
TOTW/F/M Award(s): 0
Reputation: 13
Fetus Farm is on a distinguished road
Default Re: Effects of Synthetic Pheromones on production of Natural Pheromones

Quote:
Originally Posted by Xiphoid View Post
This isn't entirely correct actually, well, to be honest, not correct at all.
Methamphetamine doesn't affect serotonin, it affects mainly dopamine but also noradrenaline. The drug does NOT contain dopamine though, when taking methamphetamine you aren't taking dopamine or a synthetic version thereof. You are taking a drug which reverses the direction of the post-synaptic transporters with the resultant effect being increased amounts of dopamine in the post-synaptic cleft and hence more stimulation of post-synaptic receptors. Methamphetamine also indirectly inhibits the re-uptake of the neurotransmitters.

So the drug isn't a synthetic chemical that does the same thing that dopamine does. It's a chemical that "tricks" the receptors into re-using the same neurotransmitters over & over instead of using once and metabolizing them. Your body doesn't stop producing dopamine though.
That was really hot. Would you consider having my babies?

But you're actually mistaken. While dopamine is probably of primary concern in the pharmacodynamics of methamphetamine, synaptic serotonin and norepinephrine levels are also affected.

Also, I believe the permanent effects of methamphetamine abuse (such as anhedonia) actually result from excitotoxic death of neurons rather than a negative feedback loop, so meth use probably isn't a good comparison. One very well documented example that's probably more appropriate is the use of corticosteroids. Use them frequently enough and without staggering dosage, and your body stops making cortisol (induced Addison's disease.)
Fetus Farm is offline   Reply With Quote
Old August 9th, 2009, 03:06 AM   #6
Xiphoid Female
Swede as Sugar
  
 
Xiphoid's Avatar
 
Join Date: Jan 2009
Location: UK
Age: 39
Posts: 1,792
Thanks: 224
Thanked 440 Times in 334 Posts
Nominated 8 Times in 7 Posts
TOTW/F/M Award(s): 0
Reputation: 1939
Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future
Default Re: Effects of Synthetic Pheromones on production of Natural Pheromones

Quote:
Originally Posted by Fetus Farm View Post
But you're actually mistaken. While dopamine is probably of primary concern in the pharmacodynamics of methamphetamine, synaptic serotonin and norepinephrine levels are also affected.
Yes, noradrenaline is also affected, like I said. Serotonin is virtually unaffected, the total effect is pretty much neglible.

Rothman, RB. et al. Therapeutics and adverse effects of serotonine transporter substrates. Pharmacol Ther 2002;95;73-85

Quote:
Also, I believe the permanent effects of methamphetamine abuse (such as anhedonia) actually result from excitotoxic death of neurons rather than a negative feedback loop, so meth use probably isn't a good comparison.
I don't know if the actual aetiology of the permanent damage caused by longterm methamphetamine abuse has been "proven" scientifically. As far as I know it's a multifactorial aetiology. One of the main causes is the down regulation of the post synaptic receptors. I wouldn't think it's a negative feedback loop, but then I never mentioned that in the first place
__________________
My toys; IS/a, IS/b, IS/b 5x cops, IH (1x & 2x), IO2x, IS (1x & 2x), CTTM2, A-nol, B-nol, Mx135, Mx202, Mx215, Mx250, Mx274, Mx282, Mx292, Mx300, TAA, TAC, TAF, TAH, TAL, EST, Meo-EST, P74, P78, P79, P80, P83, P85, P86, P90, P91, P93, P102, EOW, TUTH

Wishlist; TAK, P103, P107, Mx109, Mx216 Oh, and of course....more money....
Xiphoid is offline   Reply With Quote
Old August 9th, 2009, 09:46 AM   #7
pheropro Undisclosed
Pheromone Cadet
  
 
Join Date: May 2009
Age: 36
Posts: 21
Thanks: 0
Thanked 1 Time in 1 Post
Nominated 0 Times in 0 Posts
TOTW/F/M Award(s): 0
Reputation: 11
pheropro is on a distinguished road
Default Re: Effects of Synthetic Pheromones on production of Natural Pheromones

Quote:
Originally Posted by Fetus Farm View Post
That's not true. There are negative feedback loops in the body that do not directly involve vascular transport. For example, if you eat something that increases the acidity of your stomach, parietal cells respond by secreting less protons, thus normalizing the acidity of your stomach.

That's just one example. There are others. Unfortunately, I don't know the answer to ajo's question, but it seems like a valid concern.
Yes, it is true. Synthetic pheromones don't get ingested in any way, like, let's say a SANDWICH would. They stay on top of the skin and/or clothes.

The answer to your question is "No" Ajo.
pheropro is offline   Reply With Quote
Old August 9th, 2009, 09:55 AM   #8
Fetus Farm Undisclosed
Pheromone Enthusiast
  
 
Join Date: Aug 2009
Posts: 41
Thanks: 5
Thanked 3 Times in 3 Posts
Nominated 0 Times in 0 Posts
TOTW/F/M Award(s): 0
Reputation: 13
Fetus Farm is on a distinguished road
Default Re: Effects of Synthetic Pheromones on production of Natural Pheromones

Quote:
Originally Posted by pheropro View Post
Yes, it is true. Synthetic pheromones don't get ingested in any way, like, let's say a SANDWICH would. They stay on top of the skin and/or clothes.

The answer to your question is "No."
Uh, so what? Your argument is that because you don't ingest pheromones like a sandwich, their regulation can't possibly be regulated by a negative feedback loop? That absolutely does not follow at all.

You come off like someone who doesn't really have any grasp of the complexity of physiology. Perhaps you shouldn't attempt to make authoratative statements. You might confuse people who don't know better.
Fetus Farm is offline   Reply With Quote
Old August 9th, 2009, 01:48 PM   #9
Xiphoid Female
Swede as Sugar
  
 
Xiphoid's Avatar
 
Join Date: Jan 2009
Location: UK
Age: 39
Posts: 1,792
Thanks: 224
Thanked 440 Times in 334 Posts
Nominated 8 Times in 7 Posts
TOTW/F/M Award(s): 0
Reputation: 1939
Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future Xiphoid has a brilliant future
Default Re: Effects of Synthetic Pheromones on production of Natural Pheromones

Quote:
Originally Posted by pheropro View Post
Yes, it is true. Synthetic pheromones don't get ingested in any way, like, let's say a SANDWICH would. They stay on top of the skin and/or clothes.

The answer to your question is "No" Ajo.
Pheropro...If they only stayed on the skin, how would they then have any effect?

You may spray the phero's onto the skin, but they don't stay there, they are dissolved in a carrier liquid which diffuses The diffused phero's are inhaled by you and those around you, and from there reach the VNO. That's how you get the effects you get from phero's...they reach the VNO and stimulate neuronal receptors

The skin is the larges organ in the body btw, it's also used as one of the routes for drug delivery; Topical application of medications...
__________________
My toys; IS/a, IS/b, IS/b 5x cops, IH (1x & 2x), IO2x, IS (1x & 2x), CTTM2, A-nol, B-nol, Mx135, Mx202, Mx215, Mx250, Mx274, Mx282, Mx292, Mx300, TAA, TAC, TAF, TAH, TAL, EST, Meo-EST, P74, P78, P79, P80, P83, P85, P86, P90, P91, P93, P102, EOW, TUTH

Wishlist; TAK, P103, P107, Mx109, Mx216 Oh, and of course....more money....
Xiphoid is offline   Reply With Quote
Old August 9th, 2009, 10:31 PM   #10
OoohYahhh Male
UuuhHuh
  
 
OoohYahhh's Avatar
 
Join Date: Aug 2008
Location: Eternal Springs, TX
Posts: 686
Thanks: 122
Thanked 222 Times in 121 Posts
Nominated 12 Times in 8 Posts
Nominated TOTW/F/M Award(s): 1
Reputation: 2325
OoohYahhh has a reputation beyond repute OoohYahhh has a reputation beyond repute OoohYahhh has a reputation beyond repute OoohYahhh has a reputation beyond repute OoohYahhh has a reputation beyond repute OoohYahhh has a reputation beyond repute OoohYahhh has a reputation beyond repute OoohYahhh has a reputation beyond repute OoohYahhh has a reputation beyond repute OoohYahhh has a reputation beyond repute OoohYahhh has a reputation beyond repute
Default Re: Effects of Synthetic Pheromones on production of Natural Pheromones

Quote:
Originally Posted by Fetus Farm View Post
That's not true. There are negative feedback loops in the body that do not directly involve vascular transport. For example, if you eat something that increases the acidity of your stomach, parietal cells respond by secreting less protons, thus normalizing the acidity of your stomach.

That's just one example. There are others. Unfortunately, I don't know the answer to ajo's question, but it seems like a valid concern.
Quote:
Originally Posted by pheropro View Post
Yes, it is true. Synthetic pheromones don't get ingested in any way, like, let's say a SANDWICH would. They stay on top of the skin and/or clothes.

The answer to your question is "No" Ajo.
Quote:
Originally Posted by Fetus Farm View Post
Uh, so what? Your argument is that because you don't ingest pheromones like a sandwich, their regulation can't possibly be regulated by a negative feedback loop? That absolutely does not follow at all.

You come off like someone who doesn't really have any grasp of the complexity of physiology. Perhaps you shouldn't attempt to make authoratative statements. You might confuse people who don't know better.

Ahhh, well... it seems that you were the first person to talk about intestinal digestion.

Pheropro did ignore the the respiratory transport function, but at no point did you show any consideration of it either.

Xiphoid was kindly enough to avoid confusing people who might not know better by not making a big point about the additional effects of transdermal absorption.

Xiphoid is a brilliant woman who should be able to handily convince you that are not the smartest kid in this neighborhood. She is considerate enough (usually) not to embarass you about it. If you continue to kick up dust and the scientific big dogs show up, you will find yourself grasping for your intellectual dignity. A little more modesty and a fair bit more civility would be appropriate.

If you make the effort to do the searchs, you will find that the phyisological effects of pheromones have been the subject of discussion in this forum for a good many years. I have compiled a long series of posts and threads on the subject but, in the interest of not confusing the people that are not aware of who we are here, I will keep this brief.

Quote:
Originally Posted by tacitus View Post
haven't noticed anything in myself, other than routine pheromone burnout... if I use them too much I do become indifferent, so there appears to be a self calibration process, have concluded that the best results are from intermittant use... other than that over the last decade I have no overt physiologic symptoms or changes, nothing we can see in blood testing for natural androgen/estrogen production (I get tested for a variety of hormones and by-products, like "upstream" pregnenolone, "midstream" DHEA, "downstream" DHT, testosterone, and estrogen load)... more to the point, my PSA (prostate marker) is remarkably low, in the zero risk category... and one of the big concerns with irresponsible steroid abuse is PSA values spike... at least in my case, pheromones are demonstrating no impact on prostate volume or PSA values, even esoteric markers like SHBG (sex hormone binding globulin) which respond to excess hormone by the body pumping out more SHBG to control blood hormone levels, show no meaningful activity... No thyroid changes, no inflammation markers like TNF-a, or Interleukins show activity, no C reactive protein... no elevated liver enzymes...

If the pheromones are doing anything at the body chemistry level we can't find it in me. And we're making a serious effort to find anything out of normal ranges...

What should you do, what should everyone do ? Join the Life Extension Foundation and get their blood testing program:

lef.org


here's their testing page.. they have a ton of tests if you flip through the pages...

Life Extension Foundation: Popular Multi-Nutrient Formulas
http://www.pheromonetalk.com/mens-ph...long-3905.html


....and now you're gonna want to know what burnout is.


OoohYahhh
OoohYahhh is offline   Reply With Quote
Reply
1 Active User(s) Viewing This Topic (0 members and 1 guests):  

Tags
effects , natural , production , synthetic


Similar Threads
Thread Thread Starter Forum Replies Last Post
A question about synthetic pheromones and diet.. Jdub MEN's Pheromone Advice, Tricks and Tips 3 November 27th, 2014 01:25 PM
Hello from America! Will Pheromones decrease my natural production?? HanselPhero Introductions - New Users, Say "Hello" Today and Get $25! 3 July 31st, 2013 09:01 PM
How are synthetic pheromones/copulins made? lexy WOMEN's Pheromone Advice, Tips and Tricks 5 November 30th, 2011 11:55 AM
Is it possible to boost natural pheromone production by wearing pheromones? smoothplayer MEN's Pheromone Advice, Tricks and Tips 2 February 10th, 2007 12:34 PM

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump


All times are GMT +3. The time now is 09:37 PM.


©2004-2017 PheromoneTalk.com
(c) 2002-2015 Androtics Pheromone Research All Rights Reserved Internationally
Page generated in 0.21336 seconds with 19 queries